I won't say never to pretty much anything. I like reading and I'm willing to give most things a chance at least.
Currently not interested in Twilight though. I've still got quite some Anne Rice books to go if I want vampire drama, and what I've heard of Twilight just doesn't do anything to get me interested.
I've read a chapter or two of Shades of Grey, when a friend next to me was reading it and showing me, but they didn't do anything to make me want to read the rest of it either.
I really do want to finish The Lord of the Rings at some point but the last time I tried I got no further then the first book.
I really WANT to like it. I like it's themes and the characters, but those pages of detailed landscape descriptions and such, I have such issues getting through those. I really don't need to know about all the species of plants on a field, I just need to know it's a field....
I've had books I liked with detailed landscape descriptions, but something about Tolkien's way of writing them doesn't seem to mesh with me well.
And the Harry Potter books I've all read, I just don't think I'll be prone to rereading them anytime soon.
Somehow the ending just didn't sit well with me. I personally just.... didn't like it much for some reason, I can't really say why.
I loved the first few books but I just have no interested in reading them all again knowing I'll get to an ending I just don't really care for.
Given, good chance I'll end up reading book 3 again by itself every now and then, because I do so love Lupin's classes.