What would you do if...

[bladed]

A DREAM COME TRUE ;.; I would finally have friends!!

Hunny, we're all your friends:)   
But yes, it would be a dream come true to have ponies come to life.  iSparkle...a talking winger in my hand would literally be a-maz-ing! 

Oh, and in your hair .. though they'd have to mind their wings with me, my hair is really thick.

[Sarah-Bee]

Check number one: am I asleep?
No?
Ok, number two: am I drunk?
No?
Has someone drugged me?
No?
Have I gone mental?
Oh, I already am, ok...
 
Right then, this is happening, cool.
 
Firstly, I'd have to de-box anyone in a box (not that I have many) otherwise that would be pretty bad for them lol. Then establish the trouble makers (I'm looking at you Pinkie Pie and anyone younger than a 'regular' baby pony) and distract them with something shiny. Then I'd probably have to apologise to the work in progress customs that I've not touched for a year, and the bait box ponies too!
 
Then obviously the fun stuff! "Who did you live with before me?" and all that... and "What's it like being in a bubble mailer?"
 
It would be epic. Better still if they were all actual pony sized
 
Oh and I'd ask them to please form an orderly queue to get their hair done (by Fifi from the salon!) so that I didn't have to do it myself

[Lon-san]

Yeah, I'd grill them on where they lived before too. The 3 from the UK would probably belly-ache about how cold it was when they came to snowy Canada from sunny Austrailia.
I'd have to apologize about the mess. And hope it was only whole and finished ponies. Having the bait box come alive would be scary as hell.

[TheBeatlesPkmnFan42]

I would think I'm going mentally insane and try to remember what I ate last night. Then, if it turns out I'm not insane, I'd make sure non can escape, and I'd watch pony shows with them.
 
EDIT: I'd ask my ponies with chew marks on them how it happened.

That's sort of my webcomic is, imagining what kind of strange adventures they'd get into-- who would get along and who wouldn't, what sort of conflicts they might have.

I just had to look this up. The first page made me laugh so hard, with Firefly and Gusty fighting. The /b/ part made me lol.

[lovesbabysquirmy]

Ummmm... I would close the door to the Pony room and scream. 

Then I would probably open it and start screaming again.  Now I wouldn't be able to send them on adventures (air holes, what to write on customs forms??).  And how on earth would I afford to feed them?  Yeah...  I really don't know what I'd do...  Put them all in a wagon and start trying to adopt them to my neighbors! 

[FlitterRose]

So sweet!I would talk to them and ask my Shady is she happy with me (she can't be depressed all the time,right) Then,I'm going to talk to my favs from each an every gen.It would be great.I would also please the pegasus to lift me up in the air.