Assuming you're using Sculpey, I can't speak for any other oven bake clays, you're good to bake it as many times as you need to (but do allow it to cool between bakings). I've only done one custom with baking and I probably baked it about 50 times. I usually bake around 200 or even lower for things I plan on baking over and over again- then on the final cure I bake closer to the regular temperature for slightly longer, so as to make sure everything's fully cured and not crumbly. I have had very very thin layers of clay crack on me, but have been able to patch it up with a bit o superglue. c: