I just wanted to note that if you don't have a store on ebay, there's no method to leave an away message. If you don't want to sell anything during the time you are gone, you'd have to end all your listings in that case (I had to end all of mine for my trip.) If you're just going to be gone over the weekend, keep in mind that ebay doesn't count Sat/Sun as part of the handling time, so you could just ship anything sold on Monday.
You could edit the descriptions to say you'd be away during that time, but that most likely won't stop someone from purchasing an item :/