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Thanks guysHoM, the medicine is liquid, and he actually likes it! That made it so much easier. We presented it on a spoon and he licked it. He does not like Metacam which is the other drug but Ninja does and he's taking it as well, so when we gave them a spoon each at the same time, Simba had to lick it because Ninja did . He's only on it for two weeks so hopefully we can keep it up. It's so much easier than force it in his mouth. We were also given some chewie supplements that's supposed to destress and help with urinetractions but neither cat liked those.Simbas symptoms, except peeing is loud meowings. Around six month ago he began meowing loud after his 7pm meal, but we thought it was because he wanted to play, and it might still be, but being so loud is a symptom. He also have diarreah every now and then and barf. He is drinking more and he had lost half a kilo of weight. We hadn't noticed that because of his furr. But it all makes sense now.He has not peed in the floor since Monday! We're still hiding our rugs in a closet though.Interesting that so many of you have had cats with the same issue, or know of cats with it. It gives me hope that they lived on .