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I've never found bed bugs on any plush toys but I have found plenty of fleas.
Every time I go into a thrift store I start instinctively itching in fear, it's just ingrained in my head now. I LOVE finding things at thrift stores, but as soon as I get something, into the washer and dryer it goes, or into a hot, hot sink full of soapy water.
At goodwill we sterilized our stuffed merch with sterifab when I worked there. Never had any problems for our customers or employees.
The bedbugs or nasties you would bring home from the garage sale would be from walking around the house/property and on your clothes and your hair, far far less likely would be from the items you are buying.